What donors happen? Donor egg

Except donors of sperm, to the clinics, undertaking to help steams with struggle against barreness, are often necessary also donor eggs.

Become such donor the healthy woman from 20 till 35 years, having the healthy child can. It is very desirable, that the child at it would be not one, and a little, or even «it is more, more» - after all sometimes during delivery of a material of the lady receive damage an ovarie which can lead to barreness.

Naturally, potential donor the honey-inspection, including visiting of the therapist, the psychiatrist, the gynecologist, genetics at first will ask to pass; delivery of analyses on a HIV, a hepatitis, venereal illnesses, definition of group of blood and a Rhesus factor; an electrocardiogram and photoroentgenography. From this list it is necessary to repeat Something once a year, something - time in half a year. Besides, before each attempt take dab on degree of cleanliness of a vagina, the general analysis of urine, the blood analysis on coagulability. Payment of inspections is incurred usually by clinic.

Preparation for delivery of eggs is very difficult. Within two weeks the donor egg accepts the hormones increasing emission of eggs, and behind how these hormones influence ovaries, periodically observe by means of ultrasonic. Besides, if delivery of eggs not for frosts, and for immediate use hormones will synchronise female cycles of the donor and future mum (at which, by the way, the hormono-therapy, and too strong) is planned.

There is a question: what for to withdraw eggs directly ahead of use, whether to make it in advance is easier, to freeze them, and to store, how it and becomes, for example, with sperm? Unfortunately, no. Not all clinics can far provide conditions for storage of eggs that is why the information on donors often simply bring in a database, and only if clients choose the concrete donor, there is a delivery procedure. Naturally, there is a probability of that any concrete woman for a role of the donor never and will be not not chosen. Or will choose, but she will already change the mind by then. By the way, for the same reason eggs not always can pass semi-annual quarantine.

But to the donor egg it is heavy not only preparation for delivery of eggs - procedure too hard, it is spent at an intravenous narcosis and under the ultrasonic control. Eggs take by means of a thin hollow needle through a belly wall. Access through a vagina is sometimes possible. At least after procedure the donor should spend 2-3 hours in clinic.

To the donor egg guarantee anonymity, however about this woman the future parents nevertheless can learn something - growth, weight, a hair colour and an eye, group of blood and a Rhesus factor, a nationality, presence of a family and children. Therefore eggs to the Russian woman of average growth and the corresponding weight to hand over much easier - such gene material is in demand. Besides, the donor should not have obvious defects of appearance - large birthmarks, the asymmetrical person etc.

Naturally, it is well paid. For one procedure pay from 700 to 1000$. If the donor egg manages most to find pair, wishing to get the child by means of its eggs, to open the incognito and to correspond to all requirements of clients (appearance, age, formation, a state of health...), the compensation sum can be and more.

Barreness at some women is connected by that in their ovaries there is no growth of follicles and maturing of eggs owing to pathological conditions: a premature climax, damage of ovaries at chemotherapy and radiological treatment, a surgical trauma of ovaries, and also because of chromosomal diseases. In such cases of an egg receive from other healthy woman-donor, impregnate these donor egg sperm of the husband of the fruitless patient or sperm of the donor and the received embryos transfer to a uterus to the fruitless woman-recipient.
The program "donor eggs (oocitis)" is intended for women at whom eggs are absent or there is a high risk of a birth of children with a hereditary (genetic) pathology, and is based on fertilisation (EKO).

Experts of our Center for the first time in St.-Petersburg in 1996 have successfully carried out this program. We have the greatest experience in this area.

Volume of inspection of the married couple, decided to take advantage of a donor egg, (recipients) same, as well as at carrying out of procedure EKO.

All procedure EKO - out-patient. However, during carrying out of procedure the donor eggs can have the complications connected with operative intervention and-or application of preparations, ovaries influencing function. At their development treatment in the conditions of a hospital can be demanded. In these cases your expenses can increase in connection with expenses for treatment of the donor.
The probability of approach of pregnancy is defined by many factors and is individual in each concrete case.

There is «a Bank donor egg» which includes the surveyed healthy women till 34 years having own children. In this case the program anonymous and a choice of the donor is carried out under the description. Donor eggs can be relatives and acquaintances of a fruitless married couple. The question on absence at them contra-indications to participation in quality of donors of eggs, volume of inspection and character of preparation is defined by the head of the program after primary consultation.

Your age should be till 34 years. You should have a healthy child or children. You should not have instructions during your life on any heavy diseases and operations. If you correspond to these preliminary criteria that we could include you in ours «Bank of donors of eggs», it is necessary for you to fill personally in our Center the questionnaire and to register in reception to doctor Isakovoj Elvire Valentinovne


Definition of group of blood and Rhesus factor;
Survey of the therapist and the conclusion about a state of health and absence of contra-indications to operative intervention (it is valid 1 year);
Survey and the conclusion of the psychiatrist (unitary);
Mediko-genetic inspection - kliniko-genealogical research, etc. under indications;
Gynecologic inspection (before each attempt of an induction of superovulation);
The general analysis of urine (before each attempt of an induction of superovulation);
Electrocardiogram (it is valid 1 year);
Clinical and biochemical analyses of blood, and also the blood analysis on coagulability before each attempt of an induction of superovulation;
The blood analysis on a syphilis, a HIV, hepatitises In and With (it is valid 3 months),
Dabs on flora from an urethra and a cervikalnys of the channel and degree of cleanliness of a vagina (before each attempt of an induction of superovulation);
Inspection on an infection: a gonorrhoea, a clamidiosis, a henital herpes, an ureaplasmosis, a mycoplasmosis, (6 months are valid);
Cytologic research of dabs from a uterus neck;
Photoroentgenography (it is valid 1 year).

Donor eggs.
The donor eggs in another way are called donor eggs. In abbreviated form TO.
The first pregnancy after donor eggs has been received in 1984.
In a uterus of the woman, suffering barreness, transfer the embryos received from eggs of the woman-donor and spermatozoas of the husband or spermatozoas of the donor (cases when application of donor sperm is shown, are considered in section «Donor sperm»).

For women who do not have possibility to receive own mature egg - at an exhaustion of ovaries at any age or absence of ovaries is a unique variant to receive desired pregnancy.

Donor doctors recommend eggs also if at the woman ripen own eggs, but thus:
There were numerous attempts EKO at bad quality of received eggs and as a result received embryos of bad quality.
The bad answer to stimulation - maturing of 1-2 follicles, despite application of maximum doses FSG, and absence own ovulation cycles (when carrying out EKO in a natural cycle is possible).
High probability of transfer from mother to the future child of heavy hereditary disease.
The considerable quantity combination is inexplicable unsuccessful attempts in a combination to boundary indicators FSG and age of the woman after 39 years.
Some special individual cases. For example, extremely hard proceeding syndrome the hyperstimulations repeating processes in a uterus, contra-indications to carrying out of hyperstimulation of ovulation in the absence of contra-indications to a time pregnancy etc.

The decision on use of donor eggs is given always very hardly. It is very important not to hurry up, weigh all pro's and con's, to consult with several experts in different clinics.

But after the difficult decision is accepted, judging by experience of all our women who have come to motherhood by means of such program, that the child genetically is not native to the woman, anybody does not recollect. After reception at first positive result HG, then after the first ultrasonic and that comprehension, that inside - the new life, occurs such splash in emotions, such revaluation of all former fears, that the question native \nonnative does not rise any more.

You can not tell to anybody from relatives about that the donor egg has been used! Even to doctors who will conduct pregnancy, especially since the second trimester. Only in the first trimester special medicamentous support which to you will be appointed by your doctor who has spent EKO will be necessary. Nevertheless, to lose touch with doctor EKO to lose it is not necessary. Expediently after a birth of the child to inform doctor EKO on how there have passed your childbirth and data about the child (weight, growth, etc.).

Donor eggs usually are healthy women till 32-35 years, checked up on the infections consulted by the doctor-genetikom, having at least one healthy child.

They are specially stimulated with hormones that for a payment to give eggs to those to whom they are necessary.

In many clinics there are bases of donors of eggs, and the donor will be stimulated according to your cycle. Usually it rises in price report EKO on 500 c.u. It is a payment to the donor. I.e. the pair requiring donor eggs, completely pays preparations for stimulation of the donor, cost EKO plus the award to the donor for stimulation (on the average 500 c.u.). There are clinics where the payment to the donor depends on quantity of the received eggs.

In some clinics donor eggs are the women, which undergo procedure EKO and correspond to requirements to the donor of eggs (more often with one exception - they while do not have child).

In case of reception of a considerable quantity of mature eggs (it is more 10-12) and the consent to give 2-3 of them on the donor program, they receive the discount for carrying out of cycle EKO in 350 c.u. In such clinic and for pair to which are necessary TO program cost manages much more cheaply in comparison with clinics where special women - donors are used. In this case the pair to which are necessary TO, does not pay for medicines for stimulation (usually it is 400-800$ for stimulation of the donor). Nevertheless, in connection with development of the embryos, the given group of patients considerably decreases, since in case of an unsuccessful outcome standard the patient has chance to receive pregnancy after carrying over of the defrozen embryos.

Some doctors and fruitless steams consider, that it is better to use eggs only special women-donors, others - that application of eggs of fruitless women in programs TO is quite admissible. Each party results the arguments. But to solve all the same to you.

You can result in clinic and the donor, especially it is actual for the rare nations and nationalities. It becomes frequent enough the donor a member of a family. In this case, naturally, the donor is not anonymous.

On this question too exists two points of view: it is easier to some steams to reconcile with a genetic material (egg) from the anonymous donor, and they agree only this variant. To other steams it is easier, when they know the donor of an egg. In any case - the decision for you.

It would be desirable to advise only that the decision was accepted not in the heat of emotions, not in a condition of depression after the next unsuccessful attempt with own eggs, instead of hurrying up, after careful discussion with your second half. And it is necessary to start actions (to choose the donor, to prepare for the report) only after coincidence in sights on all questions.

Judging by experience of those whom I personally know, given birth children by means of the program TO, husbands usually enough easily agree on use of donor eggs. First, genetically is their (husbands) native children, and secondly, they to see glad at last the wives the happy.

Photos of donors usually do not show. The choice occurs by several criteria:

1. An appearance general characteristic: for example, slavic type, east etc.
2. Colour of eyes.
3. A hair colour.
4. The short description of the person: a nose, a forehead, lips etc. (this point - not in all clinics).
5. Growth, weight.
6. Group of blood and a Rhesus factor.

In some clinics the list of criteria hardly is more, in others - hardly it is less. But doctors always try, that from all blood approaching on group and a Rhesus factor of donors to pick up the most similar to you. They, unlike you, see also you, and the donor.

There are situations when formally donor not absolutely approaches (not that shade, for example, an eye or hair), but this donor is more similar to you, than the one who completely approaches under your description.

Happen, unfortunately, and cases when it is impossible and with donor eggs. Doctors recommend to change the donor after two unsuccessful attempts with fresh embryos.

Procedure EKO with TO consists in the following:

Your cycle and cycle of the woman-donor synchronise by means of hormonal preparations. Then to the donor stimulation as at usual EKO, unique difference, that sometimes stimulate the donor with cheaper preparations (it is spent does not mean stronger or more harmful as consider some!!!), and you accept preparations for preparation for successful implantation of embryos in endometrises.

Then to the woman-donor under a narcosis give the follicles, the received eggs impregnate spermatozoas of your husband (under indications - the donor), and transfer to your cavity of a uterus usually 2-3 embryos, as well as at standard EKO. Before reception of result you receive supporting therapy (use an oil solution of a progesterone (1 and 2,5 %) for intramuscular introduction).

Pregnancy presence define for 12-14 day after carrying over of embryos on concentration hg in blood plasma. At approach of pregnancy ЗGT continue to apply till 14 weeks. Adequacy of entered doses supervise on level hormones in blood. Doses steal up individually.

At donor eggs the patient does not have yellow body, but at is high-grade developing pregnancy growing horion produces chronic ganadotropin in enough. Therefore in cycles of donor eggs as a supporting preparation of an injection horagon are not appointed.

It is considered, that programs with TO are very effective. The percent of successful implantations in recalculation on a cycle at women with nonfunctioning own ovaries reaches 30 45 percent, depending on clinic.

On "Test tube" mail letters with a question on banks of eggs (by analogy to banks of sperm which are available in each EKO-CLINIC) often come. Unfortunately, egg freezing has appeared more difficult process, than preservation of embryos. And quality of the defrozen eggs, and also their ability to fertilisation, and subsequently to the further development and embryo implantation appear not so good to spend preservation in a mass order.

Eggs too freeze at necessity (for example, a puncture have made, eggs have received, and the husband could not arrive in time, or there were other any unforeseen circumstances) but that banks of eggs in a mass order (not important, donor were created or), new medical technologies are necessary.

In many centres of science work in this direction is now conducted, creation of special protectors - environments in which freezing of eggs occurs without damage of structures of cages sees perspective.

The donor eggs can be spent only under condition of full knowledge of a married couple of a treatment method, and also knowledge of the patient of the-donor of use of its eggs. An obligatory condition of carrying out donor is the voluntary consent of participants of the program and registration of corresponding documents.

In a number of the countries (Germany, Israel) for ethical and religious reasons the donor eggs are forbidden. In our country, it is not forbidden, but there is no law which would solve all ethical and legal issues of this problem.

The donor eggs are the successful program. However this method became also a victim of own success. Now a great demand for oocitises. In the conditions of deficiency of cages from clinics doubtful and inadmissible actions are possible.

Change of a donor egg to the woman for the purpose of further time pregnancy and births of the child as gynecologists-endokrinologi of our medical centre mark, most approaches those patients at whom for various reasons ovaries have been removed or are in strongly damaged condition.

It, in own way, last way to become pregnant from all medical technologies existing for today to which address when even fertilisation in laboratory conditions has not given results.

As a rule, the given procedure is spent with women, and is much more rare - at reproductive age. It is difficult enough process demanding the account of many factors and indicators, however for many it is last chance to become pregnant and give birth to the child. We will tell about change of a donor egg a little bit more in detail.

One of the most important stages of the given procedure consists in a choice of the woman-donor from which eggs will be received. The basic requirement - a good state of health, absence of chronic diseases and gross infringements in the family anamnesis.

As a rule, young women get out, is not more senior 30 - 33 years, it is desirable already having healthy children without any chromosomal anomalies and development infringements.

Use of eggs of relatives of the woman or the anonymous person who has been picked up by special medical service, prosecuting reproductive subjects is possible.

Before eggs for the subsequent fertilisation and change the woman-donor will be taken there passes strict inspection:

- Analyses on a HIV-infection, a hepatitis, infectious and inflammatory diseases of genitals.

- Survey at the therapist, the neuropathologist and some other doctors, depending on features of the family anamnesis.

After doctors have drawn a conclusion on possibility of use of eggs of the woman for change, the special contract in which she refuses any rights to the future child (children) is made, and the pair, on the contrary, incurs all legal responsibility.

Here cost of donor services and feature of payment should be stipulated. Also as the third legal side the medical institution carrying out and supervising all procedure acts, its role too should be registered in the document.

Procedure of extraction of an egg at one woman, its fertilisation in laboratory conditions and changes another has the features.

To begin with it is necessary to synchronise a menstrual cycle of the donor with a cycle of future mother that an embryo without problems a smog be fixed on a mucous membrane of a uterus and develop. For this purpose special medical products are used, in addition to the woman-donor do injections of a stimulating hormone, and to the woman-recipient enter an estrogen preparing a mucous membrane of a uterus to the future pregnancy.

As soon as cycles start to correspond each other and eggs of the donor have reached sufficient degree of a maturity, procedure of their extraction is carried out.

The local anaesthesia operating quickly is for this purpose used, and the special equipment, process passes under the ultrasonic control that does its faster and reliable.

The following stage - fertilisation in laboratory conditions (as a rule, it is used sperm of the partner of the woman-recipient), and embryo transplantation in a uterus cavity.

The mechanism of procedure same, as well as at standard fertilisation, however, as our doctors consider, chance of success all the same a little above because of use healthy eggs of the young woman.

That the embryo was attached to a mucous uterus during two - three weeks it is necessary for woman to accept hormones an estrogen and a progesterone under individually developed scheme.

Preparations can be in the form of tablets, however it is considered to be more effective intramuscular injections. The progesterone should arrive in an organism practically daily as its natural development is considerably slowed down. An estrogen appoint twice or three times a week, depending on a condition and features of functioning of hormonal system of the woman.

Speaking about efficiency of procedure of change of a donor egg, it is necessary to notice, that she gives practically the highest chances to become pregnant and give birth to the child for women after 40 years. More than half of cases terminate successfully from the first attempt, the second increases your chances to become mother even more.

The only thing that can stop pair at use of this technique - rather high cost, reaching time of ten thousand dollars. Here enters both a payment for services of doctors, and the fee of the donor. The price in many respects is contractual, based on many parametres.

Change of a donor egg means, that the impossibility to conceive the child natural by is caused by a condition of reproductive system of the woman, thus man's spermatozoas have high quality.

Unfortunately, sometimes there is an opposite situation and then not so donor egg is required, and donor sperm. Fertilisation in this case can be spent as in laboratory conditions, and внутриматочно. selection of the donor and legal aspect of procedure solve in the same way, as well as in a case with egg change.

You can always pass inspection on possibility of conception and receive a direction in the specialised centre, having addressed to accoucheurs-gynecologists or gynecologists-endokrinologam of our medical centre

Anonymous donor egg
We thank you for that you have expressed desire to become the donor and to help fruitless women, whose hopes of desired pregnancy are realizable only by means of donor eggs.

In this article we will acquaint you with donor egg process, stages of selection and check of potential donors and recipients (women whom replace an egg), a rate of commission and possible by-effects of the given procedure.

1. WHO receives my egg?

There is a set of the reasons on which some women cannot independently become pregnant. This congenital absence of ovaries, their removal by surgical operations, an early menstrual pause. However such woman can take out pregnancy if to it the donor egg is replaced. Besides, some women are carriers of serious genetic diseases which can be transferred to their children. With reception of a "healthy" egg the risk of transfer of these diseases disappears. To the third category of women for which donor eggs are necessary, fruitless women with eggs of bad quality concern. It mostly women aged are more senior 40 years which are already close to a menstrual pause. Chances to become pregnant and give birth to the healthy child at such women increase to 70 % if it replace a healthy egg of the young woman.

2. WHO and how can become the donor eggs?

The woman at the age of 20-30 years, wishing to help fruitless steams by participation in the donor egg program. The donor should be a normal constitution (without excess weight), to have own healthy children, not to smoke, not to suffer gynecologic and other diseases. It passes full inspection on presence of such diseases, as a HIV, a syphilis, a hepatitis In and With, a gonorrhoea, a clamidiosis, a mycoplasmosis, an ureaplasmosis, a cytomegalovirus, a henital herpes. Besides, it is surveyed by the therapist and there passes interview with the psychologist.

3. How I can become donor eggs?

For our card file the woman fills the special form and represents the recent photo. These data are stored in strict confidentiality. The photo allows to select the potential donors most suitable to external signs and recipients.
During the first reception the doctor will discuss with you a condition of your health, ultrasonic for an estimation of the general state of health and a condition of your ovaries will inspect also. During the following visit you will hand over blood and dab for the subsequent analyses. After reception of results of inspection you will meet the psychologist who will carry out the psychological analysis and will discuss with you psychological aspects of a donor service.

Then selection of suitable recipients is spent. After that you can begin participation in the program.

4. What process of a donor service, after acknowledgement of my participation in the program?

After you were chosen by any married couple, your medical procedures are synchronised with procedures of the woman-recipient. To you can appoint contraceptive tablets within 1 month before the beginning of medical process. A following medicine which you will accept - the DIFERELIN.

In a natural menstrual cycle monthly after has begun menstruations some eggs start to grow, but only one egg continues the development till a full maturity and ovulation. The remained eggs which have started to develop, stop development and resolve in ovaries. Applying ganadotropins, we can "rescue" these eggs and compel them to finish the process of maturing. It allows to collect more than one mature egg for fertilisation in laboratory.

The egg develops in a follicle - the vial filled with a liquid. The follicle grows in process of maturing of eggs. We have possibility to define how your eggs in reply to ganadotropins quickly develop, spending ultrasonic for definition of the size of growing follicles. Ganadotropins are entered by a hypodermic injection, as well as diferelins, or an intramuscular injection (into area of a muscle of a hip). You will prick ganadotropins once a day, continuing thus diferelin injections. The injection of ganadotropins should do daily during 4х days, and for 5th day to come to clinic for repeated ultrasonic. 1-2 ultrasonics within 8-10 days can be necessary for you to define the best day for gathering of eggs.

After results of ultrasonic will show, that eggs have ripened, it will be necessary for you to make last prick - a preparation of pregnils. It is an intramuscular injection in a hip muscle. Pregnils gives a signal to eggs to definitive maturing that they could be impregnated. In laboratory. If not to enter this preparation there will be no normal fertilisation of eggs. The doctor will ask to make you an injection a pregnil during strictly certain time (for example, at 11 o'clock in the evening) so that gathering of eggs to make exactly in 35 hours after introduction of this preparation.

Procedure of gathering of eggs occupies about 10 minutes and is spent in a handling room.
You should come for 30 minutes prior to the beginning of procedure. After midnight before a puncture of eggs it is impossible to drink and accept food. As it was spoken above, eggs ripen in the vials (cysts) filled with a liquid named follicles. We can take ripened eggs from your ovaries, directing a narrow needle through a vagina wall is direct in follicles and supervising this process on the screen of the ultrasonic device. To take an egg, we exhaust a liquid from follicles. The needle has little bit more diameter, than a needle for gathering of blood from a vein. We try to take eggs from each large follicle in both ovaries. Usually we manage to collect 10-20 eggs.

Directly ahead of procedure of gathering of eggs the anaesthesiologist will make to you intravenous anaesthesia. Procedure will pass under full anaesthesia, therefore you will not test painful discomfort.

After the termination of procedure you should have a rest within 1-2 hours. The special chamber is for this purpose provided. Then you will be free and can go home after payment of your services. As you had an anaesthesia, it is better, that somebody has taken you home. You should not sit down a wheel till next day. To work it is possible to return next day. Sexual relations it is possible to renew after following menstruations. With following menstruations can, if want, to renew reception of contraceptive tablets.

5. I will receive what indemnification for the participation?

Before the beginning of the program of a donor egg with you the contract consists. Thus your participation in the donor egg program is paid. For each cycle of a donor service to you pay 600 dollars (in roubles) in day of a puncture of eggs.

6. Whether there will come at me a menstrual pause before term after delivery of my eggs?

At the 12-year-old girl in ovaries is about 300 000 eggs. For genital years in process of ovulation by ovaries it is spent less than 500 of them. The remained 299 500 eggs are exposed to process under the name «atresya» at which they, not ripening, resolve in ovaries between the period of approach of a sexual maturity and a menstrual pause. In connection with presence of a considerable quantity of these "spare" eggs, there are no bases to believe, that the drug intake during donor process, or an in itself donor egg can reduce stocks of eggs in such degree to lead to an early menstrual pause.

7. What possible by-effects of a donor egg?

The small percent (less than 10 %) the women accepting a diferelin and ganadotropins, finds out such time by-effects from these medicines, as a headache, hypostases and frequent differences of mood. They disappear with the drug intake termination. Medical process is the big stress for our fruitless patients because of their huge desire to become pregnant, and the stress strengthens these symptoms. As you do not pass through the same strong stress during a drug intake, you are less subject to any of these by-effects.

Process of gathering of eggs is connected with very insignificant risk of bleedings and infections. It is very improbable, that you will lose more than a teaspoon of blood during extraction of eggs. And the risk of damage of belly bodies a needle for gathering of eggs is even less. For protection against infections during procedure we give you an antibiotic. The probability of a bleeding or infection occurrence is extremely small, much less, than 1 to 1000. At one of the doctors of our clinic having experience in EKO about 12 years, it was never observed similar complications.
At some women after last injection a pregnil some days are observed an insignificant swelling of a stomach. It is called as a syndrome of hyperstimulation of ovaries. Doctors will attentively track your reaction to medical products by results of ultrasonic and will take all necessary measures to lower probability of occurrence of these complications. The stomach swelling usually completely passes within 10 days after gathering of eggs. In very rare cases (less than 1 %) the patient can be hospitalised for inspection.

7. How many time it is possible to hand over eggs as the donor?

In Russia there are no methodical recommendations of Ministry of Health about this question as the donor egg has no long-term by-effects. In our practice we follow recommendations of the American Society of Reproductive Medicine where it is specified, that the donor can hand over the eggs to six times.

8. What should be having rummaged between donor service cycles?

Theoretically eggs it is possible to hand over each menstrual cycle (every month), but we do at least a two-month break between donor service cycles to give rest to ovaries of the donor.

9. How my anonymity is observed?

All information on donor programs is stored in the safe of the head physician.
The married couple receiving your eggs, signs the statement that they undertake not to establish the person of the donor of eggs and understand, that their further communications, or their children, with you are impossible. They will not know your name. But it will give the general information concerning your weight, growth, appearance, a national identity and history of illnesses in a family.

In summary

We hope, that this the information has helped you to understand better the responsibility connected with process donor eggs, and all procedure which it is necessary to pass thus. Your donor service becomes an invaluable gift to those fruitless steams for whom the unique chance to become pregnant is to become pregnant by means of voluntary participation of such women, as you.

Anonymous donor service of eggs in EKO to clinic
If you have expressed desire to become the donor and to help fruitless women, whose hopes of desired pregnancy are realizable only by means of donor eggs, this information for you.

Many women do not know about existence of such way to help fruitless women and to earn money, as a donor service of oocitises.

In this section we will acquaint you with process donor egg, stages of selection and check of potential donors and recipients (women whom replace an egg), a rate of commission and possible by-effects of the given procedure.

There is a set of the reasons on which some women cannot independently become pregnant. This congenital absence of ovaries, their removal by surgical operations, an early menstrual pause. However such woman can take out pregnancy if to it the donor egg is replaced. Besides, some women are carriers of serious genetic diseases which can be transferred to their children. With reception of a "healthy" egg the risk of transfer of these diseases disappears. To the third category of women for which donor eggs are necessary, fruitless women with eggs of bad quality concern. It mostly women aged are more senior 40 years which are already close to a menstrual pause. Chances to become pregnant and give birth to the healthy child at such women increase to 70 % if it replace a healthy egg of the young woman.


The woman at the age of 20-30 years, wishing to help fruitless steams by participation in the program donor eggs. The donor should be a normal constitution (without excess weight), to have own healthy children, not to smoke, not to suffer gynecologic and other diseases. The donor passes full inspection on presence of such diseases, as a HIV, a syphilis, a hepatitis In and With, a gonorrhoea, a clamidiosis, a mycoplasmosis, an ureaplasmosis, a cytomegalovirus, a henital herpes. Besides, the donor is surveyed by the therapist and there passes interview with the psychologist.


If you have expressed desire to become donor egg (oocitises) you can leave a brief information on here.

With you our expert who will answer all questions interesting you will necessarily communicate, will organise carrying out of inspection and preparation for the program donor eggs.

During the first reception the doctor will discuss with you a condition of your health, ultrasonic for an estimation of the general state of health and a condition of your ovaries will inspect also. You will hand over blood and dab for the subsequent analyses. After reception of results of inspection you will meet the psychologist who will carry out the psychological analysis and will discuss with you psychological aspects of a donor service. All medical consultations and inspections for the donor are spent free of charge!!!

Besides, the donor fills the special form and represents the recent photo. These data are stored in strict confidentiality. The photo allows to select the potential donors most suitable to external signs and recipients.

What process of a donor service, after acknowledgement of my participation in the program?

After you were chosen by any married couple, your medical procedures are synchronised with procedures of the woman-recipient. To you can appoint contraceptive tablets within 1 month before the beginning of medical process. A following medicine which you will accept - a diferelin.

Its action is directed on time decrease in development by an organism of hormones i.e. the substances developed by a hypophysis, - gland located in the basis of a brain and influencing ovaries. Appointment of this preparation allows the doctor to carry out the control of maturing of eggs better. The preparation is entered daily by a hypodermic injection by means of very thin needle (same, as an insulin needle for diabetics). In 7-10 days after the beginning of introduction of a preparation to you will make ultrasonic for check of readiness of your ovaries to a following stage of the program. This very day to you will appoint the following preparation - Ganadotropin.

In a natural menstrual cycle monthly after has begun menstruations some eggs start to grow, but only one egg continues the development till a full maturity and ovulation. The remained eggs which have started to develop, stop development and resolve in ovaries. Applying ganadotropins, we can "rescue" these eggs and compel them to finish the process of maturing. It allows to collect more than one mature egg for fertilisation in laboratory.

The egg develops in a follicle - the vial filled with a liquid. The follicle grows in process of maturing of eggs. We have possibility to define how your eggs in reply to ganadotropins quickly develop, spending ultrasonic for definition of the size of growing follicles. Ganadotropins are entered by a hypodermic injection, as well as diferelins, or an intramuscular injection (into area of a muscle of a hip). You will enter ganadotropins once a day, continuing thus diferelin injections. The injection of ganadotropins should do daily within 4 days, and for 5th day to come to clinic for repeated ultrasonic. 1-2 ultrasonics within 8-10 days can be necessary for you to define the best day for gathering of eggs. In one of days of carrying out of ultrasonic you will need to receive consultation of the anaesthesiologist. On this consultation personally for you the method of anaesthesia and preparation for a prospective narcosis will be picked up.

After results of ultrasonic will show, that eggs have ripened, it will be necessary for you to make last prick - a preparation of pregnils. It is an intramuscular injection in a hip muscle. Pregnils gives a signal to eggs to definitive maturing that they could be impregnated in laboratory. If not to enter this preparation, there will be no normal fertilisation of eggs. The doctor will ask to make you an injection a pregnil during strictly certain time (for example, at 11 o'clock in the evening) so that gathering of eggs to make exactly in 35 hours after introduction of this preparation.

Procedure of gathering of eggs occupies about 10 minutes and is spent in a handling room. You should come for 1 hour prior to the beginning of procedure. After midnight it is impossible to drink and accept food.

As it was spoken above, eggs ripen in the vials (cysts) filled with a liquid named follicles. Eggs are taken from follicles an ovarie by means of the thin needle entered through a wall of a vagina under the control of ultrasonic. The needle has little bit more diameter, than a needle for gathering of blood from a vein. We try to take eggs from each large follicle in both ovaries. Usually we manage to collect 10-20 eggs.

Directly ahead of procedure of gathering of eggs the anaesthesiologist will make to you intravenous anaesthesia. Procedure will pass under full anaesthesia, therefore you will not test painful discomfort.

After the termination of procedure you should have a rest in chamber 1-2 hours. Then you will be free and can go home after payment of your services. As you had an anaesthesia, it is better, that somebody has taken you home. You should not sit down a wheel till next day. To work it is possible to return next day. Sexual relations it is possible to renew after following menstruations. From the beginning of a following menstrual cycle it is possible to renew reception of contraceptive tablets.


You receive material indemnification for participation in the program donor egg about what with you the contract before the program beginning consists. For each cycle of a donor service to you pay monetary compensation. Payment is made by two parts: the first part is paid right after to a puncture, the second at visiting of the doctor after next menstruations for the purpose of an estimation of a condition of ovaries and reception of recommendations.

Whether there will come at me a menstrual pause before term after delivery of my eggs?

At the 12-year-old girl in ovaries is about 300 000 eggs. For genital years in process of ovulation by ovaries it is spent less than 500 of them. The remained 299 500 eggs are exposed to process under the name "atresia" at which they resolve in ovaries between the period of approach of a sexual maturity and a menstrual pause. In connection with presence of a considerable quantity of these "spare" eggs, there are no bases to believe, that the drug intake during donor process, or an in itself donor service of eggs can reduce stocks of eggs in such degree to lead to an early menstrual pause.


The small percent (less than 10 %) the women accepting a diferelin and ganadotropins, finds out such time by-effects, as a headache, hypostases and frequent differences of mood. They disappear with the drug intake termination. Medical process is the big stress for our fruitless patients because of their huge desire to become pregnant, and the stress strengthens these symptoms. As you do not pass through the same strong stress during a drug intake, you are less subject to any of these by-effects.

Process of gathering of eggs is connected with very insignificant risk of bleedings and infections. During extraction of eggs blood loss makes no more than one teaspoon. The risk of damage of belly bodies a needle for gathering of eggs is minimum. For protection against infections during procedure antibiotics are appointed. The probability of a bleeding or infection occurrence is extremely small, much less, than 1:1000.

At some women after last injection a pregnil some days are observed an insignificant swelling of a stomach and a pain in the field of ovaries. It is called as a syndrome of hyperstimulation of ovaries. Doctors will attentively track your reaction to medical products by results of ultrasonic and will take all necessary measures to lower probability of occurrence of these complications. The stomach swelling usually completely passes within 10 days after gathering of eggs. In very rare cases (less than 1 %) the patient can be hospitalised for inspection. In this case it is not necessary to accept independent decisions, your doctor will help you with hospitalisation in specialised clinic where the help at the highest professional level will be rendered you.

To define, whether ovaries to the normal condition have returned, it is necessary to visit the doctor for control ultrasonic and reception of necessary recommendations.

How many time it is possible to hand over eggs as the donor?

In Russia there are no methodical recommendations of Ministry of Health about this question as the donor service of eggs has no long-term by-effects. In our practice we follow recommendations of the American Society of Reproductive Medicine where it is specified, that the donor can hand over the eggs to six times.

What should be having rummaged between donor service cycles?

Theoretically eggs it is possible to hand over each menstrual cycle (every month), but we do at least a two-month break between donor service cycles to give rest to ovaries of the donor.

How my anonymity is observed?

All information on donor programs is especially confidential. The married couple receiving your eggs, signs the statement that they undertake not to establish the person of the donor of eggs and understand, that their further communications, or their children, with you are impossible. They will not know your name. But it will give the general information concerning your weight, growth, appearance, a national identity and history of illnesses in a family.

We hope, that this the information has helped you to understand better the responsibility connected with process donor egg, and all procedure which it is necessary to pass thus. Your donor service becomes an invaluable gift to those fruitless steams for whom the unique chance to become pregnant is to become pregnant by means of voluntary participation of such women, as you.

If you have expressed desire to become donor eggs (oocitises) you can leave a brief information on here.

With you the expert who will answer all questions interesting you will necessarily communicate, will organise carrying out of inspection and preparation for the program donor egg.

Become frequent the woman cannot mum for the objective reasons. We will tell, if it has transferred operation on removal of a uterus or ovaries. Or age any more that. In this case programs eko are inefficient. It is necessary to resort to donor egg - to use cages of other woman.

The donor eggs (oocitis) are one of kinds of programs of fertilisation. Feature is use of eggs of young healthy women - donors.

To a donor service resort in two cases. When reception of own eggs is impossible or when oocitises are, but their quality leaves much to be desired.

The first group. It is possible to carry women who do not have ovaries or appendages to it. Women concern the same group with a syndrome of a premature exhaustion of function of ovaries and a syndrome of resistant ovaries.

The second group are women at whom all the same it is possible to receive own oocitises under certain conditions, however use of these cages is inexpedient because of bad quality or possibility of transfer of hereditary diseases. Usually it is patients of the senior reproductive age - after 37-40 years at which the stock is physiologically lowered. Or women at whom in programs EKO received poor quality eggs that led to unsuccessfulness of programs EKO.


By the Russian legislation donors of eggs can be young healthy women till 35 years which have own children and there are no diseases. There are two kinds of a donor service: anonymous and not the anonymous. In the first case the donor is unfamiliar with future mum and the donor service is carried out anonymously. Not the anonymous donor service means acquaintance of a married couple to the donor and carrying out of the joint program.


After carrying out of careful inspection of the donor and future mum the doctor, using special preparations, achieves synchronism of menstrual cycles of both women. After that to the donor preparations which cause growth and development of follicles are appointed. When follicles will reach the sizes of 18-20 mm, receive eggs which then are impregnated sperm of the husband by women-RECIPIENTS.

While the donor accepts stimulating preparations, to the patient the hormonal means promoting preparation an endometris to carrying over of embryos and their further implantation are appointed.

Contra-indications to a donor eggs

Diseases of the woman when pregnancy can worsen its condition, and also oncological diseases can be medical contra-indications.

Features of conducting pregnancy after programs donor egg

1. The technique is that, that we is artificial we form a cycle to the woman-retsipientke. Thus it does not have own ovulation so, and the yellow body which synthesises a hormone of pregnancy a progesterone is not formed. Therefore progesterone preparations are necessary for accepting as supporting therapy.

2. Whether pregnancy tearing away is possible? After all the fruit is genetically absolutely alien to an organism of women. Fortunately, the nature has thought up the mechanism which interferes with tearing away. At pregnancy approach the immune system of mother chokes, and the organism starts to develop protective antibodies which do not allow cages - to killers to attack "another's" cages.

1. Indications for carrying out EKO with use donor eggs:

The absence of oocitises caused by a natural menstrual pause, syndrome of a premature exhaustion of ovaries, a condition after removal of ovaries, radio-or chemotherapy, and also anomalies of development;

Functional inferiority eggs at the women having genetic infringements who can be transferred to posterity;

Inefficiency of several before the spent attempts standard EKO at the insufficient answer of ovaries to ovulation stimulation, numerous reception of embryos of the poor quality which carrying over does not lead to pregnancy approach.

2. Contra-indications:

Somatic and mental diseases at which there are contra-indications for a time pregnancy;

Congenital developmental anomalies or the got deformations of a cavity of a uterus at which implantation of embryos is impossible;

Tumours of ovaries;

Hyperplastic processes an endometris;

The good-quality tumours of a uterus demanding operative treatment;

Sharp inflammatory diseases of any localisation;

Malignant new growths of any localisation, including in the anamnesis.

3. Donors eggs can be:

Relatives and acquaintances of recipients,
Anonymous professional donors.

At an anonymous professional donor egg between medical centre VRT and the donor the contract which represents the informed consent to carrying out of an induction of superovulation, punctures of ovaries consists. In the contract obligations of the parties also are defined.

Age from 20 till 34 years;

Presence of own healthy child;

Absence bright a fenotips of features.

4. The program "a donor egg" includes following stages:

Synchronisation of menstrual cycles of the donor and the recipient;

Stimulation of ovulation of the donor by means of ganadotropins;

Puncture of ovaries. Fertilisation of the received eggs by sperm of the husband;

Carrying over of embryos.

5. Volume of inspection of a married couple before EKO.

To both spouses:

Photoroentgenography (it is valid 1 year);

The blood analysis on group and a Rhesus factor;

The blood analysis on RW, an antigene to a hepatitis In, antibodies to a virus of a hepatitis With (it is valid 3 months).

For the wife:

The blood analysis, including coagulability time (1 month is valid);

The general analysis of urine;

Dabs on flora, cytologic research of dabs from a uterus neck;

The general and special gynecologic inspection;

Ultrasonic research of bodies of a small basin;

The conclusion of the therapist about a state of health and time pregnancy possibility.

Under indications:

Blood hormones: FSG, LG, a prolaktins, a testosteron, TTG, Т4, antibodies to a thyroid gland;

Research of a material a channel cervikalnys on hlamids, mycoplasmas, ureaplasmas, trichomonads (it is valid 6 MES;

Inspection on presence an antispermal and an antifosfolifids of antibodies.

For the husband:

Spermogram, trial processing of sperm, sperm morphology.

6. Volume of inspection of professional donors of oocitises.

Gynecologic inspection, ultrasonic of bodies of a small basin;

Dab on flora from an urethra and a cervikalnys of the channel and degree of cleanliness of a vagina;

Dab on cytology from a uterus neck;

Inspection on an infection: a gonorrhoea, a clamidiosis, a henital herpes, an ureaplasmosis, a mycoplasmosis, a cytomegalovirus;

The blood analysis on a syphilis, a HIV, hepatitises In and With;

Definition of group of blood and Rhesus factor;

The clinical analysis of blood;

The blood analysis on coagulability;

The biochemical analysis of blood: ALT, ACT, bilirubin, sugar, urea;

The general analysis of urine;

ELECTROCARDIOGRAM;

Photoroentgenography;

Survey of the therapist and the conclusion about a state of health and absence of contra-indications to operative intervention;

Survey and the conclusion of the psychiatrist;

The blood analysis on kariotipses;

Survey and the conclusion genetics

7. Cost of program EKO with donor oocitises develops of several components:

Inspection of the donor egg;

Synchronisation of menstrual cycles of the recipient and the donor egg;

Carrying out of an induction of superovulation of the donor by ganadotropins;

Program EKO and carrying over of embryos to a cavity of a uterus recipients.

As there is a donor egg

Donor eggs for the woman who do not have children for any reasons have suggested to become me. Whether it is possible to learn, how this donor service occurs (and that it in general such) from you, the expert. To me 33 years, I have 12 summer children. Money is necessary. I will be very grateful to learn opinion of the knowing person on this question.

From you take an egg a thin needle under the ultrasonic control (you almost will not feel anything). Before survey on all parametres, will cure if that, will wait on ultrasonic by which will do every day, maturing of an egg and besides under the ultrasonic control will make a puncture an ovarie, take an egg and will release you. And an egg will place in a nutrient medium and will start up to it spermatozoas. The embryo which for 3-5 day besides a needle will place to other woman in a uterus is then formed.

You will sign papers according to which you will not apply for the parental rights and will not search for the child, to learn about it etc. to It never certainly too about you will tell.

In Clinic programs with donor eggs are spent. The matter is that at some Women, wishing to become happy mum, there are no own eggs or in general there are no ovaries (are removed during operation). For such Women the program with a donor egg becomes unique chance of motherhood. Fertilisation of female cages occurs «in a test tube» method EKO sperm of the husband of the Woman, a germ will place in a uterus of the Woman. So the Woman will bear pregnancy, and then and to give birth to the child.

Donor egg - voluntary business. In Clinic the program "Anonymous donor service" is spent. At the same time the Woman can take advantage of the program «not Anonymous donor service» (give eggs relatives or girlfriends of the Woman can).

Become donor eggs in Clinic any woman can, at observance of following conditions:

Age from 20 till 30 years.

Presence of own HEALTHY children.

Absence of such diseases as a HIV, a syphilis, hepatitises.

Absence of contra-indications from the general health: diseases of internal bodies in an aggravation stage, and also mental frustration.

Absence of sexual infections, including hidden.

Absence of the expressed features of a structure of a skeleton.

Absence of hereditary diseases in a family.

Absence of diseases of genitals which can become aggravated under the influence of program EKO. For example, uterus myomas, cysts an ovarie, an endometriosis, etc.

Presence of unconditional possibility within two weeks regularly to visit clinic for passage of program EKO.


In the beginning the woman comes on primary reception to the doctor-reprodutologu who talks to it, explaining to feature of the future donor service. The doctor also finds out its above described features, together with specific features. Besides, to the Donor spend gynecologic survey to estimate a condition of sexual system.

Then full inspection according to the existing standard is spent
"About application of auxiliary reproductive technologies in therapy of female and man's barreness"). Whether Only the doctor can solve the candidate for a donor approaches.

The program for the Donor consists of reception of medical products within 2 weeks, surveys in clinic and receptions of eggs from an organism.

Stimulation is spent by HORMONAL preparations - but it at all those hormones about which the bad glory goes: a pier, «moustaches will grow, the cellulitis will jump out, monthly will come to an end». On the contrary, introduction of female sexual hormones positively affects appearance of the woman.

After 2 weeks after the beginning of the program the doctor receives eggs at the Donor by a puncture of follicles.

For puncture carrying out use the general narcosis, duration of 2-4 minutes. The puncture is a small operation which is spent through a vagina wall. On end of all procedures and survey by the doctor the Donor in some hours leaves Clinic. UNIQUE restriction after a puncture - an interdiction for driving of the car within days.

All features of mutual relations between Clinic and donor egg are fixed in the Contract and the informed consent from the Donor on carrying out of medical procedures. Payment of an anonymous donor service is spent after a puncture.

Many women require the help of the Donor. To become donor eggs is means to help the Woman to find great happiness to become Mum!

Donor egg anonymous

Donor egg it is used when ovaries of the patient owing to the various reasons do not develop own eggs or at repeated unsuccessful attempts of methods of artificial fertilisation. Donor eggs also it is used in medicine at risk of transfer to the child of hereditary illnesses.
Who can be donor egg?

Donor egg there can be a woman aged till 35 years, possessing good physical and mental health. The donor service program eggs is completely anonymous. The spouses using donor eggs cannot see a photo of the donor, and the factor, presence of a family and children, a nationality are only informed on such parametres of the donor as growth, weight, a hair colour and an eye, group of blood and a Rhesus factor.

It is desirable, that age of the recipient (the patient using donor eggs) was till 50 years. Ovules it is not given to the donor to any information on the recipient.
When the donor service egg is used?
Indications for carrying out in vitro with use donor the ovules are:

-Absence eggs for such reasons, as natural menstrualpause, a syndrome of a premature exhaustion of ovaries, removal of appendages of a uterus.
-Presence at the patient of a gene with a mutation and the hereditary diseases linked to a floor.
- Unsuccessful attempts in vitro, low reaction of ovaries to an induction ovulation, numerous reception of embryos of poor quality.

Volume of inspection of donors egg

1 group of blood + a Rhesus factor
2 survey of the psychiatrist
3 full gynecologic inspection
4 photoroentgenography
5 analyses of blood on a HIV, RW, hepatit In and With
6 definition Ig G and M on a cytomegalovirus, a herpes virus (once a year)
7 dab on cleanliness degree
8 bacteriological inspection of a material cervikals the channel: hlamids, a mycoplasma, an ureaplasma, the trichomonad, a gonorrhoea
9 dab on patology from a uterus neck
10 research kariotips
11 molekuljarno-genetic research on presence mukovisiciozs.


Donor egg there can be healthy women with normal appearance from 20 till 35 years, having healthy children, it can be even the relative or the acquaintance of the recipient. It is desirable, that the woman did not plan to have more children, as in process probably damage ovarie, including leading to barreness.

Delivery of eggs - much more difficult procedure, than sperm delivery. Besides not all clinics can far provide due storage of eggs and consequently prefer to have base of donors, and cages to withdraw directly ahead of application.

The first pregnancy with use of donor egg has been received in 1984. The first child who has developed from the frozen egg, was born only in December, 2005.

At first the woman-donor is surveyed by the doctor (the therapist, the psychiatrist, the gynecologist), it hands over analyses on a HIV, a hepatitis, venereal illnesses. To it do an electrocardiogram and photoroentgenography (these researches are valid 1 year so if the woman already was exposed to them to bring results enough). Also the group of blood and a Rhesus factor is defined. Before each attempt dab on degree of cleanliness of a vagina, the general analysis of urine, the blood analysis on coagulability also surrenders.
Documents with which fills donor eggs, are similar to that for the donor of sperm. Unless in the questionnaire it is underlined also the size of a breast, and the maintenance of the voluntary informed consent of the donor differs a little.
The fertilisation method in vitro If the donor approaches, to it throughout two weeks apply hormonal therapy on purpose to increase quantity of the formed eggs. Of growth and degree of readiness of eggs observe by means of ultrasonic. If use of eggs at once (without frosts) it is added also hormonal correction of female cycles for their synchronisation at the donor and at future mother (such preparation can occupy some months) is planned.

When eggs ripen, them take through a belly wall by means of thin hollow game (at an intravenous narcosis and under the ultrasonic control). In some cases access through a vagina is possible. Extraction of eggs is made under the general anaesthesia, in 2-3 hours the donor can already leave clinic.
The world of Councils pays your attention that the basic risk for health consists in existence of probability of excessive stimulation of ovaries, up to their rupture. Complications from hormonal therapy or damage of ovaries in the course of actually withdrawal of eggs are possible also.
For one procedure pay 700-1000$ depending on clinic. Also some clinics offer the insurance on a case of occurrence of problems with health owing to stimulation by hormones.