Donor eggs.
The donor eggs in another way are called donor eggs. In abbreviated form TO.
The first pregnancy after donor eggs has been received in 1984.
In a uterus of the woman, suffering barreness, transfer the embryos received from eggs of the woman-donor and spermatozoas of the husband or spermatozoas of the donor (cases when application of donor sperm is shown, are considered in section «Donor sperm»).

For women who do not have possibility to receive own mature egg - at an exhaustion of ovaries at any age or absence of ovaries is a unique variant to receive desired pregnancy.

Donor doctors recommend eggs also if at the woman ripen own eggs, but thus:
There were numerous attempts EKO at bad quality of received eggs and as a result received embryos of bad quality.
The bad answer to stimulation - maturing of 1-2 follicles, despite application of maximum doses FSG, and absence own ovulation cycles (when carrying out EKO in a natural cycle is possible).
High probability of transfer from mother to the future child of heavy hereditary disease.
The considerable quantity combination is inexplicable unsuccessful attempts in a combination to boundary indicators FSG and age of the woman after 39 years.
Some special individual cases. For example, extremely hard proceeding syndrome the hyperstimulations repeating processes in a uterus, contra-indications to carrying out of hyperstimulation of ovulation in the absence of contra-indications to a time pregnancy etc.

The decision on use of donor eggs is given always very hardly. It is very important not to hurry up, weigh all pro's and con's, to consult with several experts in different clinics.

But after the difficult decision is accepted, judging by experience of all our women who have come to motherhood by means of such program, that the child genetically is not native to the woman, anybody does not recollect. After reception at first positive result HG, then after the first ultrasonic and that comprehension, that inside - the new life, occurs such splash in emotions, such revaluation of all former fears, that the question native \nonnative does not rise any more.

You can not tell to anybody from relatives about that the donor egg has been used! Even to doctors who will conduct pregnancy, especially since the second trimester. Only in the first trimester special medicamentous support which to you will be appointed by your doctor who has spent EKO will be necessary. Nevertheless, to lose touch with doctor EKO to lose it is not necessary. Expediently after a birth of the child to inform doctor EKO on how there have passed your childbirth and data about the child (weight, growth, etc.).

Donor eggs usually are healthy women till 32-35 years, checked up on the infections consulted by the doctor-genetikom, having at least one healthy child.

They are specially stimulated with hormones that for a payment to give eggs to those to whom they are necessary.

In many clinics there are bases of donors of eggs, and the donor will be stimulated according to your cycle. Usually it rises in price report EKO on 500 c.u. It is a payment to the donor. I.e. the pair requiring donor eggs, completely pays preparations for stimulation of the donor, cost EKO plus the award to the donor for stimulation (on the average 500 c.u.). There are clinics where the payment to the donor depends on quantity of the received eggs.

In some clinics donor eggs are the women, which undergo procedure EKO and correspond to requirements to the donor of eggs (more often with one exception - they while do not have child).

In case of reception of a considerable quantity of mature eggs (it is more 10-12) and the consent to give 2-3 of them on the donor program, they receive the discount for carrying out of cycle EKO in 350 c.u. In such clinic and for pair to which are necessary TO program cost manages much more cheaply in comparison with clinics where special women - donors are used. In this case the pair to which are necessary TO, does not pay for medicines for stimulation (usually it is 400-800$ for stimulation of the donor). Nevertheless, in connection with development of the embryos, the given group of patients considerably decreases, since in case of an unsuccessful outcome standard the patient has chance to receive pregnancy after carrying over of the defrozen embryos.

Some doctors and fruitless steams consider, that it is better to use eggs only special women-donors, others - that application of eggs of fruitless women in programs TO is quite admissible. Each party results the arguments. But to solve all the same to you.

You can result in clinic and the donor, especially it is actual for the rare nations and nationalities. It becomes frequent enough the donor a member of a family. In this case, naturally, the donor is not anonymous.

On this question too exists two points of view: it is easier to some steams to reconcile with a genetic material (egg) from the anonymous donor, and they agree only this variant. To other steams it is easier, when they know the donor of an egg. In any case - the decision for you.

It would be desirable to advise only that the decision was accepted not in the heat of emotions, not in a condition of depression after the next unsuccessful attempt with own eggs, instead of hurrying up, after careful discussion with your second half. And it is necessary to start actions (to choose the donor, to prepare for the report) only after coincidence in sights on all questions.

Judging by experience of those whom I personally know, given birth children by means of the program TO, husbands usually enough easily agree on use of donor eggs. First, genetically is their (husbands) native children, and secondly, they to see glad at last the wives the happy.

Photos of donors usually do not show. The choice occurs by several criteria:

1. An appearance general characteristic: for example, slavic type, east etc.
2. Colour of eyes.
3. A hair colour.
4. The short description of the person: a nose, a forehead, lips etc. (this point - not in all clinics).
5. Growth, weight.
6. Group of blood and a Rhesus factor.

In some clinics the list of criteria hardly is more, in others - hardly it is less. But doctors always try, that from all blood approaching on group and a Rhesus factor of donors to pick up the most similar to you. They, unlike you, see also you, and the donor.

There are situations when formally donor not absolutely approaches (not that shade, for example, an eye or hair), but this donor is more similar to you, than the one who completely approaches under your description.

Happen, unfortunately, and cases when it is impossible and with donor eggs. Doctors recommend to change the donor after two unsuccessful attempts with fresh embryos.

Procedure EKO with TO consists in the following:

Your cycle and cycle of the woman-donor synchronise by means of hormonal preparations. Then to the donor stimulation as at usual EKO, unique difference, that sometimes stimulate the donor with cheaper preparations (it is spent does not mean stronger or more harmful as consider some!!!), and you accept preparations for preparation for successful implantation of embryos in endometrises.

Then to the woman-donor under a narcosis give the follicles, the received eggs impregnate spermatozoas of your husband (under indications - the donor), and transfer to your cavity of a uterus usually 2-3 embryos, as well as at standard EKO. Before reception of result you receive supporting therapy (use an oil solution of a progesterone (1 and 2,5 %) for intramuscular introduction).

Pregnancy presence define for 12-14 day after carrying over of embryos on concentration hg in blood plasma. At approach of pregnancy ЗGT continue to apply till 14 weeks. Adequacy of entered doses supervise on level hormones in blood. Doses steal up individually.

At donor eggs the patient does not have yellow body, but at is high-grade developing pregnancy growing horion produces chronic ganadotropin in enough. Therefore in cycles of donor eggs as a supporting preparation of an injection horagon are not appointed.

It is considered, that programs with TO are very effective. The percent of successful implantations in recalculation on a cycle at women with nonfunctioning own ovaries reaches 30 45 percent, depending on clinic.

On "Test tube" mail letters with a question on banks of eggs (by analogy to banks of sperm which are available in each EKO-CLINIC) often come. Unfortunately, egg freezing has appeared more difficult process, than preservation of embryos. And quality of the defrozen eggs, and also their ability to fertilisation, and subsequently to the further development and embryo implantation appear not so good to spend preservation in a mass order.

Eggs too freeze at necessity (for example, a puncture have made, eggs have received, and the husband could not arrive in time, or there were other any unforeseen circumstances) but that banks of eggs in a mass order (not important, donor were created or), new medical technologies are necessary.

In many centres of science work in this direction is now conducted, creation of special protectors - environments in which freezing of eggs occurs without damage of structures of cages sees perspective.

The donor eggs can be spent only under condition of full knowledge of a married couple of a treatment method, and also knowledge of the patient of the-donor of use of its eggs. An obligatory condition of carrying out donor is the voluntary consent of participants of the program and registration of corresponding documents.

In a number of the countries (Germany, Israel) for ethical and religious reasons the donor eggs are forbidden. In our country, it is not forbidden, but there is no law which would solve all ethical and legal issues of this problem.

The donor eggs are the successful program. However this method became also a victim of own success. Now a great demand for oocitises. In the conditions of deficiency of cages from clinics doubtful and inadmissible actions are possible.